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New onset and exacerbations of psoriasis following COVID-19 vaccines: a systematic review

Oxidative stress plays a prominent role in SARS-CoV-2 infection following recognition of the viral S-protein by angiotensin converting enzyme-2 receptor and pattern recognition receptors like toll-like receptors 2 and 4, and activation of transcription factors like nuclear factor kappa B, that subsequently activate nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) expression succeeded by ROS production

Prescriptions for these medications surged by over 300% from 2018 to 2023

Vitamin E, especially its form known as -tocopherol, is a strong antioxidant, important for the prevention of oxidation of unsaturated fatty acids in cell membranes [49, 50]